Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process
نویسندگان
چکیده
منابع مشابه
Cation binding to 15-TBA quadruplex DNA is a multiple-pathway cation-dependent process
A combination of explicit solvent molecular dynamics simulation (30 simulations reaching 4 µs in total), hybrid quantum mechanics/molecular mechanics approach and isothermal titration calorimetry was used to investigate the atomistic picture of ion binding to 15-mer thrombin-binding quadruplex DNA (G-DNA) aptamer. Binding of ions to G-DNA is complex multiple pathway process, which is strongly a...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 2011
ISSN: 1362-4962,0305-1048
DOI: 10.1093/nar/gkr639